S.No. Sequence_definition HRE_location_on_sequence HRE sequence HRE (A|G)CGTG) HAS (CA(C|G)(A|G)(T|G|C)) 1 >Aldoa, Mus musculus, NC_000073.6, minus Geneid: 11674 1527..1557 ACGTGTCCCATCTCTTACCCAGGCCATGAT ACGTG CAGGC 2 >ENO1, Homo sapiens, NC_000001.11, minus Geneid: 2023 4708..4738 ACGTGGCCCCGGACACGCAGCGCTGCGGCG ACGTG CACGC 3 >EPO, Bos taurus, AC_000182.1, minus Geneid: 280784 2496..2526 ACGTGAGTGTGCGTGTGTTTGTCCCACAGC GCGTG CACAG 4 >EPO, Bos taurus, AC_000182.1, minus Geneid: 280784 2294..2324 GCGTGAGGGGAGAGGCAGGTCCCACAGCCC GCGTG CAGGT 5 >EPO, Bos taurus, AC_000182.1, minus Geneid: 280784 2506..2536 GCGTGTGTTTGTCCCACAGCTGGGATCCTG GCGTG CACAG 6 >HMOX1, Bos taurus, AC_000162.1, plus Geneid: 513221 2234..2264 ACGTGGACAAAACAGAGATGAAAATCACAG ACGTG CAGAG 7 >HMOX1, Homo sapiens, NC_000022.11, plus Geneid: 3162 2338..2368 GCGTGAAGTCTCTGCACATAGTAAATTCTC GCGTG CACAT 8 >LDHB, Homo sapiens, NC_000012.12, minus Geneid: 3945 4271..4301 GCGTGTTTGTTGAAACAGGTTGAAAAAAAT GCGTG CAGGT 9 >VEGFA, Bos taurus, AC_000180.1, plus Geneid: 281572 1183..1213 ACGTGGGATCTTAGTTCCCAGAGCAGGGAT ACGTG CAGAG 10 >VEGFA, Bos taurus, AC_000180.1, plus Geneid: 281572 3930..3960 ACGTGGGCTCCAACAGGTCCTCTTCTCTCT ACGTG CAGGT 11 >VEGFA, Bos taurus, AC_000180.1, plus Geneid: 281572 4193..4223 ACGTGGGACCACTCGAGTCCCAGACGTGCC ACGTG CAGAC 12 >VEGFA, Homo sapiens, NC_000006.12, plus Geneid: 7422 3925..3955 ACGTGGGCTCCAACAGGTCCTCTTCCCTCC ACGTG CAGGT 13 >VEGFA, Homo sapiens, NC_000006.12, plus Geneid: 7422 4635..4665 GCGTGTCTCTGGACAGAGTTTCCGGGGGCG GCGTG CAGAG 14 >Vegfa, Mus musculus, NC_000083.6, minus Geneid: 22339 3977..4007 ACGTGGGTTTCCACAGGTCGTCTCACTCCC ACGTG CAGGT 15 >aldoa, Salmo salar, NC_027302.1, minus Geneid: 100380798 4680..4710 ACGTGAGATCTGTCACGTACATGATCACAA ACGTG CACGT 16 >eno1, Takifugu rubripes, NC_018892.1, minus Geneid: 101069815 4554..4584 ACGTGACCCCCGGTCCCACGTGACTAACAA ACGTG CACGT 17 >epo, Salmo salar, NC_027306.1, plus Geneid: 106608895 4229..4259 GCGTGGCTGTGTCTCCCAGACATCAGGCTA GCGTG CAGAC 18 >epoa, Danio rerio, NC_007118.6, minus Geneid: 100004455 2070..2100 ACGTGGCCAGCTTAACCCAGACGAGCATCA ACGTG CAGAC 19 >epoa, Danio rerio, NC_007118.6, minus Geneid: 100004455 4903..4933 ACGTGCACTATGCGACAGGGAACATCATAG ACGTG CAGGG 20 >hmox1a, Danio rerio, NC_007114.6, minus Geneid: 791518 2815..2845 GCGTGTTTATATTTCAGATACTTACTGAGA GCGTG CAGAT 21 >hmox1a, Danio rerio, NC_007114.6, minus Geneid: 791518 3143..3173 GCGTGGTTATAGTGGACACAGTTCACGCCT GCGTG CACAG 22 >igfbp1, Takifugu rubripes, NC_018911.1, minus Geneid: 101074885 1144..1174 ACGTGAGAAGCAGGCAGAGGAAAAAACAAA ACGTG CAGAG 23 >igfbp1, Takifugu rubripes, NC_018911.1, minus Geneid: 101074885 2631..2661 GCGTGGGCACCGTGACCACATCTTCAGTGG GCGTG CACAT 24 >igfbp1, Takifugu rubripes, NC_018911.1, minus Geneid: 101074885 4143..4173 GCGTGGGTGAGCACAGCACAGAATCTGATC GCGTG CACAG 25 >igfbp1a, Danio rerio, NC_007131.6, minus Geneid: 317638 86..116 GCGTGTGCTGACGCTCACAGGCTGTTTCAC GCGTG CAGGC 26 >vegfa, Takifugu rubripes, NC_018905.1, plus Geneid: 101073237 3331..3361 ACGTGCAGGATTGTGCAGATGCAGGGGAGT ACGTG CAGAT 27 >vegfa, Takifugu rubripes, NC_018905.1, plus Geneid: 101073237 4570..4600 ACGTGTCCGGCTGCACACGCTTTTATTATA ACGTG CACGC 28 >vegfaa, Danio rerio, NC_007127.6, minus Geneid: 30682 4966..4996 GCGTGTTAACATCCACGGCAGTACGAACCA GCGTG CACGG Functional HRE in reverse strand -------------------------------------------------- S.No. Sequence_definition HRE_location_on_sequence HRE sequence HRE (A|G)CGTG) HAS (CA(C|G)(A|G)(T|G|C)) 1 >ENO1, Homo sapiens, NC_000001.11, minus Geneid: 2023 274..304 GCGTGTCCGGGGCCACGTGCGCCGCCTGCG GCGTG CACGT 2 >EPO, Homo sapiens, NC_000007.14, plus Geneid: 2056 4047..4077 ACGTGCACCATCACACTCACATCCACACAT ACGTG CACAT 3 >EPO, Homo sapiens, NC_000007.14, plus Geneid: 2056 230..260 GCGTGAGGGGTCGCCAGGGGTAGGGGCCAC GCGTG CAGGG 4 >EPO, Homo sapiens, NC_000007.14, plus Geneid: 2056 306..336 GCGTGAGCGGGGCTGCTGCAGACGTGCGTG GCGTG CAGAC 5 >Epo, Mus musculus, NC_000071.6, minus Geneid: 13856 335..365 GCGTGAGGGGTCGCCAGAGGTGGGGGCCAC GCGTG CAGAG 6 >HMOX1, Homo sapiens, NC_000022.11, plus Geneid: 3162 2891..2921 GCGTGTATAGATCCAGAGTCTGTCCATTCA GCGTG CAGAG 7 >HMOX1, Homo sapiens, NC_000022.11, plus Geneid: 3162 889..919 GCGTGGGACACTCTTCCAGGCACATTCAGG GCGTG CACAT 8 >IGFBP1, Homo sapiens, NC_000007.14, plus Geneid: 3484 882..912 GCGTGCCATGCTCCAGGCCTGCCCCTTGGT GCGTG CAGGC 9 >LDHB, Homo sapiens, NC_000012.12, minus Geneid: 3945 3488..3518 GCGTGCTGGCAGTCCTCACAGCCCTCCCTG GCGTG CACAG 10 >Vegfa, Mus musculus, NC_000083.6, minus Geneid: 22339 726..756 GCGTGTTTCTGACATACACACACACCCAAA GCGTG CACAC 11 >aldoa, Salmo salar, NC_027302.1, minus Geneid: 100380798 302..332 ACGTGACAGATCTCACGTGCATAATGCATG ACGTG CACGT 12 >aldoa, Salmo salar, NC_027302.1, minus Geneid: 100380798 338..368 ACGTGCCCGTGATATACAGCCACAGCAGAA ACGTG CACAG 13 >aldoa, Takifugu rubripes, NC_018890.1, plus Geneid: 101071185 4597..4627 ACGTGAGCTGTACAGAGTAGCTGCGCCTGA ACGTG CAGAG 14 >eno1, Takifugu rubripes, NC_018892.1, minus Geneid: 101069815 375..405 ACGTGCAGGGATGCAGGCAGGGATGTCGAT ACGTG CAGGG 15 >eno1, Takifugu rubripes, NC_018892.1, minus Geneid: 101069815 4042..4072 ACGTGTGGGATGTGTCTCAGGGGAGGGGAG ACGTG CAGGG 16 >eno1, Takifugu rubripes, NC_018892.1, minus Geneid: 101069815 425..455 ACGTGGGACCGGGGGTCACGTTTTTGCCAC ACGTG CACGT 17 >eno1, Takifugu rubripes, NC_018892.1, minus Geneid: 101069815 367..397 GCGTGAGTACGTGCAGGGATGCAGGCAGGG GCGTG CAGGG 18 >hmox1, Takifugu rubripes, NC_018906.1, minus Geneid: 101070079 1050..1080 GCGTGAGCCAGCAGATTTCACGGACGCGTT GCGTG CACGG 19 >hmox1, Takifugu rubripes, NC_018906.1, minus Geneid: 101070079 417..447 GCGTGTCAGCTGCTGCCAGGTCATCAGAAA GCGTG CAGGT 20 >hmox1, Takifugu rubripes, NC_018906.1, minus Geneid: 101070079 619..649 GCGTGTTGCACAAACAGCACATAATATACA GCGTG CACAT 21 >hmox1a, Danio rerio, NC_007114.6, minus Geneid: 791518 1229..1259 GCGTGGGTTTACTCAGGGTGTTCCGGTTTC GCGTG CAGGG 22 >igfbp1, Takifugu rubripes, NC_018911.1, minus Geneid: 101074885 4057..4087 ACGTGGGCCGTGTCCATCTCAGAGACACGA ACGTG CAGAG 23 >igfbp1a, Danio rerio, NC_007131.6, minus Geneid: 317638 1192..1222 ACGTGACCTCACTCAGGTCAGGACGGCACC ACGTG CAGGT 24 >ldhb, Takifugu rubripes, NC_018907.1, plus Geneid: 101079766 2955..2985 ACGTGTTCACACTCAGACTGAAGCAGGTTT ACGTG CAGAC 25 >ldhba, Danio rerio, NC_007115.6, minus Geneid: 30497 396..426 GCGTGCACGCCACACACCTGAAGGCATTTT GCGTG CACAC 26 >vegfa, Takifugu rubripes, NC_018905.1, plus Geneid: 101073237 410..440 GCGTGTGCAGCCGGACACGTATACCAACCG GCGTG CACGT