S.No.	Sequence_definition	HRE_location_on_sequence	HRE sequence	HRE (A|G)CGTG)	HAS (CA(C|G)(A|G)(T|G|C))
1	>HMOX1, Bos taurus, AC_000162.1, plus Geneid: 513221	2234..2264	ACGTGGACAAAACAGAGATGAAAATCACAG	ACGTG	CAGAG
2	>HMOX1, Homo sapiens, NC_000022.11, plus Geneid: 3162	2338..2368	GCGTGAAGTCTCTGCACATAGTAAATTCTC	GCGTG	CACAT
3	>hmox1a, Danio rerio, NC_007114.6, minus Geneid: 791518	2815..2845	GCGTGTTTATATTTCAGATACTTACTGAGA	GCGTG	CAGAT
4	>hmox1a, Danio rerio, NC_007114.6, minus Geneid: 791518	3143..3173	GCGTGGTTATAGTGGACACAGTTCACGCCT	GCGTG	CACAG

Functional HRE in reverse strand 
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S.No.	Sequence_definition	HRE_location_on_sequence	HRE sequence	HRE (A|G)CGTG)	HAS (CA(C|G)(A|G)(T|G|C))
1	>HMOX1, Homo sapiens, NC_000022.11, plus Geneid: 3162	2891..2921	GCGTGTATAGATCCAGAGTCTGTCCATTCA	GCGTG	CAGAG
2	>HMOX1, Homo sapiens, NC_000022.11, plus Geneid: 3162	889..919	GCGTGGGACACTCTTCCAGGCACATTCAGG	GCGTG	CACAT
3	>hmox1, Takifugu rubripes, NC_018906.1, minus Geneid: 101070079	1050..1080	GCGTGAGCCAGCAGATTTCACGGACGCGTT	GCGTG	CACGG
4	>hmox1, Takifugu rubripes, NC_018906.1, minus Geneid: 101070079	417..447	GCGTGTCAGCTGCTGCCAGGTCATCAGAAA	GCGTG	CAGGT
5	>hmox1, Takifugu rubripes, NC_018906.1, minus Geneid: 101070079	619..649	GCGTGTTGCACAAACAGCACATAATATACA	GCGTG	CACAT
6	>hmox1a, Danio rerio, NC_007114.6, minus Geneid: 791518	1229..1259	GCGTGGGTTTACTCAGGGTGTTCCGGTTTC	GCGTG	CAGGG